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The vision-related burden of dry eye
- Source :
- Ocular Surface, 23, 207-215. ELSEVIER SCIENCE BV
- Publication Year :
- 2022
-
Abstract
- Purpose: To investigate the relationship between dry eye disease (DED) and vision-related quality of life (VR-QoL) at population level.Methods: DED and VR-QoL were assessed in 89,022 participants (18–96 years, 59% female) from the Dutch population-based Lifelines cohort using the Women's Health study (WHS) and Visual function 25 (VFQ25) questionnaires. The relationship between DED and compromised VR-QoL was assessed with logistic regression, corrected for age, sex, BMI, income, education, smoking, and 55 comorbidities.Results: 9.1% of participants had DED. The participants with DED had higher risk of compromised average of ten domains of VR-QoL (OR 3.12 (95% CI 2.98–3.27) corrected for age, sex, BMI, income, smoking, and 55 comorbidities). Increasing symptom frequency was highly associated with decreasing VR-QoL (P < 0.0005). In all VR-QoL domains, including measures of daily visual function and emotional well-being, DED was clearly associated with compromised VR-QoL. Compared to macular degeneration, glaucoma, retinal detachment, and allergic conjunctivitis, DED presented similar or higher risks for compromised score on all VR-QoL domains. The population-attributable fraction of DED for compromised general vision exceeded that of other eye diseases investigated, especially in the younger age groups.Conclusion: DED is associated with reductions in all domains of VR-QoL, also after correction for associated comorbidities. We found that DED imposes an extensive population burden regarding compromised VR-QoL due to its high prevalence and substantial impact on VR-QoL, higher than that for other common vision-affecting eye disorders. Our results emphasize the importance of recognizing DED as a serious disorder from both patient and public health perspectives.
- Subjects :
- Male
medicine.medical_specialty
Vision-related quality of life (VR-QoL)
Visual function
Population
Disease
Logistic regression
Cohort Studies
Quality of life
Population attributable fraction
Surveys and Questionnaires
Medicine
Humans
Dry eye disease
education
education.field_of_study
business.industry
Public health
Glaucoma
humanities
Ophthalmology
Cohort
Quality of Life
Eye disorder
Dry Eye Syndromes
Female
business
Demography
Driving
Subjects
Details
- Language :
- English
- ISSN :
- 15420124
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Ocular Surface
- Accession number :
- edsair.doi.dedup.....917b362b35b989a8cff447d1f4f9e107