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Magnetic resonance features of sinonasal melanotic mucosal melanoma
- Source :
- BMJ Case Rep
- Publication Year :
- 2019
-
Abstract
- A 67-year-old man presented to ear, nose and throat department complaining of nasal congestion and recurrent epistaxis for 5 months. Nasal endoscopy revealed a pigmented polyp obstructing the right nasal cavity. MRI with contrast agent showed a right nasal cavity polypoid mass with hyper signal intensity (SI) both in non-enhanced T1-w and diffusion imaging, marked hypo SI in T2-w sequences and avidly contrast enhancement characterised by rapid wash-in without significant wash-out on dynamic perfusion imaging. Histological specimen showed epithelioid and spindle cells with focal intense pigmentations and immunohistochemical features compatible with primary melanotic sinonasal mucosal melanoma (SNM). As melanotic SNM shows MRI pathognomonic high non-enhanced T1-w SI, this case underlines the crucial role of MRI not only in assessing the local tumour extension/recurrence but also in increasing the diagnostic confidence of detecting melanotic SNM. Thus, MRI should be always performed in case of clinical–endoscopic suspicion of SNM.
- Subjects :
- Male
Pathology
medicine.medical_specialty
Nose Neoplasms
Perfusion scanning
Pigmentations
Nasal congestion
03 medical and health sciences
0302 clinical medicine
Rare Disease
Positron Emission Tomography Computed Tomography
medicine
otorhinolaryngologic diseases
Humans
Magnetic Resonance Imaging
melanoma
Nasal polyps
030223 otorhinolaryngology
Melanoma
Nose
Aged
Neoplasm Staging
medicine.diagnostic_test
business.industry
Head and neck cancer
Mucosal melanoma
Magnetic resonance imaging
General Medicine
medicine.disease
Pancreatic Neoplasms
Nasal Mucosa
medicine.anatomical_structure
030220 oncology & carcinogenesis
medicine.symptom
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- BMJ Case Rep
- Accession number :
- edsair.doi.dedup.....920c9db326c8369c7c85e516f580e22a