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Causes of failure of pallidal deep brain stimulation in cases with pre-operative diagnosis of isolated dystonia

Authors :
Jana K. Boller
Martin Südmeyer
Constanze E. Kämpfer
Christoph Schrader
Juergen Voges
Thomas Liebig
Rainer Benecke
Mohammad Maarouf
Joachim K. Krauss
Elena Moro
Faycal El Majdoub
K. Amande M. Pauls
Wolfgang Fogel
Andrea A. Kühn
Gereon R. Fink
Niels Allert
Kailash P. Bhatia
Philipp Mahlknecht
Jens Volkmann
Josef Kessler
Christian Blahak
Matthias Wittstock
Joerg Mueller
Lars Timmermann
Alexander Wolters
Source :
Parkinsonism & related disorders 43, 38-48 (2017). doi:10.1016/j.parkreldis.2017.06.023
Publication Year :
2017
Publisher :
Elsevier Science, 2017.

Abstract

IntroductionPallidal deep brain stimulation (GPi-DBS) is an effective therapy for isolated dystonia, but 10–20% of patients show improvement below 25–30%. We here investigated causes of insufficient response to GPi-DBS in isolated dystonia in a cross-sectional study.MethodsPatients with isolated dystonia at time of surgery, and

Details

Language :
English
Database :
OpenAIRE
Journal :
Parkinsonism & related disorders 43, 38-48 (2017). doi:10.1016/j.parkreldis.2017.06.023
Accession number :
edsair.doi.dedup.....92be6f76775ea9b5f450a778c16b529d
Full Text :
https://doi.org/10.1016/j.parkreldis.2017.06.023