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Size of thyroid carcinoma by histotype and variants: A population-based study in a mildly iodine-deficient area
- Source :
- Headneck. 39(10)
- Publication Year :
- 2016
-
Abstract
- Background Data relating the size of thyroid cancer with histological types and variants are scarce. Methods All incident thyroid cancer diagnosed between 2003 and 2012 in a mildly iodine-deficient area were derived from a population-based tumor registry. Undifferentiated/anaplastic thyroid cancer and incidental cases were excluded. Major diameter of thyroid cancer, as assessed by pathological examination, was stratified in classes: ≤10 mm; 11-20 mm; 21-40 mm; and >40 mm. For each class, absolute and relative frequencies of histological types were calculated. Results Tumors >20 mm were more frequent among follicular thyroid carcinoma (FTC) and Hurthle cell carcinoma than in other histotypes, with median size of 22.50 mm (95% confidence interval [CI] 16.71-28.29) and 25.00 mm (95% CI 17.04-32.96) in FTC and Hurthle cell carcinoma, respectively. Odds ratio for tumors >20 mm was significant for FTC and Hurthle cell carcinoma only (P < .0001). Conclusion Among the histotypes and variants of differentiated thyroid cancer, FTC and Hurthle cell carcinoma are characterized by the largest size.
- Subjects :
- Adult
Male
Pathology
medicine.medical_specialty
Population
Thyroid Gland
030209 endocrinology & metabolism
Thyroid carcinoma
03 medical and health sciences
Young Adult
0302 clinical medicine
medicine
Humans
Registries
Thyroid Neoplasms
Anaplastic thyroid cancer
education
Thyroid cancer
Aged
Retrospective Studies
education.field_of_study
business.industry
Thyroid
Histology
Odds ratio
Middle Aged
medicine.disease
medicine.anatomical_structure
Otorhinolaryngology
Italy
030220 oncology & carcinogenesis
Population study
Female
business
Iodine
Subjects
Details
- ISSN :
- 10970347
- Volume :
- 39
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Headneck
- Accession number :
- edsair.doi.dedup.....92dcb08d77e082853045762a38e36161