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Prognostic Models for Renal Cell Carcinoma in the Era of Immune Checkpoint Therapy

Authors :
Andreea Parosanu
Ioana Miruna Stanciu
Cristina Pirlog
Cristina Orlov Slavu
Horia Cotan
Cristian Iaciu
Ana Maria Popa
Mihaela Olaru
Oana Moldoveanu
Baston Catalin
Cornelia Nitipir
Source :
Cureus. 14(10)
Publication Year :
2022

Abstract

With recent advances in oncology, immune checkpoint inhibitors (ICIs) have become a milestone in immuno-oncology. Unfortunately, although ICIs have demonstrated improved clinical efficacy in a broad spectrum of cancers, many patients do not respond to this newer therapy. As a result, it is crucial to identify predictive factors of response to immunotherapy in patients with kidney cancer. This review discusses the research investigating potential biomarkers of response to ICIs in renal cell carcinoma.

Subjects

Subjects :
General Engineering

Details

ISSN :
21688184
Volume :
14
Issue :
10
Database :
OpenAIRE
Journal :
Cureus
Accession number :
edsair.doi.dedup.....931b95fdb74188b0eb3d1b681ae0aced