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Outcome of transition phase patients with juvenile idiopathic arthritis
- Source :
- Modern Rheumatology. 28:832-837
- Publication Year :
- 2018
- Publisher :
- Oxford University Press (OUP), 2018.
-
Abstract
- Objectives: Across diagnosis groups, successful transition of adolescent and young adults from children's hospitals to adult care is often associated with decreased treatment adherence and treatment results. The aim of this study was to characterize disease activity and anti-rheumatic medications following transfer of care of juvenile idiopathic arthritis (JIA) patients to the adult clinic.Method: All consecutive JIA patients aged 16-20 years who visited the specific transition clinic in the rheumatology outpatient clinic of Helsinki University Hospital between November 2012 and May 2013 and between April 2015 and April 2016 were evaluated.Results: A total of 214 patients were identified, and 23 appeared in both cohorts. Females had higher disease activity scores (DAS) than males (DAS28-CRP 1.90.7 versus 1.6 +/- 0.3, p=.019; and DAS44-CRP 1.0 +/- 0.7 versus 0.7 +/- 0.5, p=.005; respectively) in the latter cohort. Disease-modifying antirheumatic drugs (DMARDs) were prescribed to 86% of patients, and 48% were on biological DMARDs (bDMARDs), whereas 14% had no specific treatments.Conclusion: Disease activity and clinic attendance remained stable during the transition period. The proportion of transition phase JIA patients on bDMARDs was high and disease activity was low. Reasons for lower disease activity in males in the latter cohort require further investigation.
- Subjects :
- Male
Pediatrics
medicine.medical_specialty
Adolescent
Treatment adherence
Arthritis
CATEGORIES
Adult care
Adolescents
smoking
THERAPIES
Young Adult
03 medical and health sciences
0302 clinical medicine
transition of care
Rheumatology
Quality of life
QUALITY-OF-LIFE
3123 Gynaecology and paediatrics
YOUNG-ADULTS
disease-modifying antirheumatic drugs
medicine
Humans
DISEASE-ACTIVITY SCORE
Juvenile
COHORT
030212 general & internal medicine
Young adult
030203 arthritis & rheumatology
business.industry
FINLAND
medicine.disease
HLA-B27 PREDICTS
Arthritis, Juvenile
RHEUMATOID-ARTHRITIS
3. Good health
CLINICAL REMISSION
Antirheumatic Agents
3121 General medicine, internal medicine and other clinical medicine
Rheumatoid arthritis
Cohort
Female
juvenile idiophatic arthritis
business
Subjects
Details
- ISSN :
- 14397609 and 14397595
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Modern Rheumatology
- Accession number :
- edsair.doi.dedup.....93f6eb32b19cc7c0478d1ae82bda69ff