Gelatin/polyvinyl alcohol loaded magnesium hydroxide nanocomposite attenuates neurotoxicity and oxidative stress in Alzheimer's disease induced rats

Authors :: Manickam, Rajkumar
Karuppaiya, Vimala
Darwin Dasan, Tamiliniyan
Ramasundaram, Thangaraj
Ramakrishnan, Jaganathan
Poomani, Kumaradhas
Soundarapandian, Kannan
Source :: International Journal of Biological Macromolecules. 222:2122-2143
Publication Year :: 2022
Publisher :: Elsevier BV, 2022.
Abstract: Amyloid-β (Aβ) plaque formation, neuronal cell death, mitochondrial and cholinergic dysfunction are key indicators of Alzheimer's disease (AD). In this study, gelatin and polyvinyl alcohol (PVA) were tethered with magnesium hydroxide (Mg(OH)

Subjects :: Magnesium Hydroxide
Amyloid beta-Peptides
Cholinergic Agents
General Medicine
Biochemistry
Antioxidants
Streptozocin
Rats
Nanocomposites
Oxidative Stress
Disease Models, Animal
Alzheimer Disease
Structural Biology
Polyvinyl Alcohol
Spectroscopy, Fourier Transform Infrared
Animals
Gelatin
Molecular Biology

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