Investigating the efficacy and safety of metronidazole during pregnancy; A systematic review and meta-analysis

Authors :: Anil Uzunali
Emmanuelle Ripoche
Emilie Vittaz
Patrick Maison
Thierry Vial
Priscilla Ajiji
Agence nationale de sécurité du médicament et des produits de santé [Saint-Denis] (ANSM)
Epidemiology in Dermatology and Evaluation in Therapeutics (EpiDermE)
Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)
Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS)
Hospices Civils de Lyon (HCL)
VO, alexandra
Source :: European Journal of Obstetrics & Gynecology and Reproductive Biology: X, Vol 11, Iss, Pp 100128-(2021), European Journal of Obstetrics & Gynecology and Reproductive Biology: X, European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 2021, 11, pp.100128. ⟨10.1016/j.eurox.2021.100128⟩
Publication Year :: 2021
Publisher :: Elsevier, 2021.
Abstract: International audience; Objective: We aimed to review and analyze studies focusing on the efficacy of metronidazole in reducing the risk of preterm birth and the safety of metronidazole taking into account the different doses, duration of treatment and routes of administration.Study designs: Embase, Cochrane Library and PubMed were searched up to 29 July 2019 to identify studies assessing metronidazole exposure during pregnancy. Additional studies were identified from reference lists of retrieved papers. Measured outcomes were preterm births (

Language :: English
ISSN :: 25901613
Volume :: 11
Database :: OpenAIRE
Journal :: European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Accession number :: edsair.doi.dedup.....94747d2d9bac6afd559c7af211d91c97
Full Text :: https://doi.org/10.1016/j.eurox.2021.100128⟩

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