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Advances in Functional Imaging of Differentiated Thyroid Cancer
Advances in Functional Imaging of Differentiated Thyroid Cancer
- Source :
- Cancers, Cancers, Vol 13, Iss 4748, p 4748 (2021)
- Publication Year :
- 2021
- Publisher :
- MDPI, 2021.
-
Abstract
- Simple Summary Since the 1940s, radioactive iodine has been used for functional imaging and for treating patients with differentiated thyroid cancer (DTC). During this long-lasting experience, the use of iodine isotopes evolved, especially during the last years due to improved knowledge of thyroid cancer biology and improved performances of imaging tools. The present review summarizes recent advances in the field of functional imaging and theragnostic approach of DTC. Abstract The present review provides a description of recent advances in the field of functional imaging that takes advantage of the functional characteristics of thyroid neoplastic cells (such as radioiodine uptake and FDG uptake) and theragnostic approach of differentiated thyroid cancer (DTC). Physical and biological characteristics of available radiopharmaceuticals and their use with state-of-the-art technologies for diagnosis, treatment, and follow-up of DTC patients are depicted. Radioactive iodine is used mostly with a therapeutic intent, while PET/CT with 18F-FDG emerges as a useful tool in the diagnostic management and complements the use of radioactive iodine. Beyond 18F-FDG PET/CT, other tracers including 124I, 18F-TFB and 68Ga-PSMA, and new methods such as PET/MR, might offer new opportunities in selecting patients with DTC for specific imaging modalities or treatments.
- Subjects :
- Cancer Research
medicine.medical_specialty
Radioiodine uptake
diagnosis
differentiated thyroid cancer
Review
Imaging modalities
medicine
Diagnosis
Differentiated thyroid cancer
Imaging
Radioactive iodine therapy
Theragnostic
Therapeutic intent
Thyroid cancer
RC254-282
business.industry
theragnostic
Fdg uptake
Thyroid
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
imaging
medicine.disease
radioactive iodine therapy
Functional imaging
medicine.anatomical_structure
Oncology
Radiology
Radioactive iodine
business
Subjects
Details
- Language :
- English
- ISSN :
- 20726694
- Volume :
- 13
- Issue :
- 19
- Database :
- OpenAIRE
- Journal :
- Cancers
- Accession number :
- edsair.doi.dedup.....94784e359abec0a04c6e6c86c95b8137