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Defining prognostic factors of survival after external beam radiotherapy treatment of hepatocellular carcinoma with lymph node metastases
- Source :
- Clinicaltranslational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 15(9)
- Publication Year :
- 2012
-
Abstract
- To identify independent predictors of survival in patients with lymph node (LN) metastases from hepatocellular carcinoma (HCC) after external beam radiotherapy (EBRT). There were 191 patients with LN metastases from HCC received EBRT enrolled in the study cohort. EBRT was designed to focus on the LNs and a median dose of 50 Gy (range 40–60 Gy) was delivered. Treatment response was assessed by the WHO response criteria. Factors such as demographic data, tumor characteristics, and treatment modalities were determined before EBRT. Predictors of survival were identified by univariate and multivariate analysis. The median survival was 8.0 months for all patients. Factors including Child-Pugh status (p = 0.009), intrahepatic tumor control (p = 0.015), LN location (p = 0.015), and response to EBRT (p
- Subjects :
- Oncology
Adult
Male
Cancer Research
medicine.medical_specialty
Multivariate analysis
Carcinoma, Hepatocellular
Time Factors
medicine.medical_treatment
Metastasis
Internal medicine
medicine
Carcinoma
Humans
External beam radiotherapy
Neoplasm Metastasis
Lymph node
Aged
Proportional Hazards Models
Aged, 80 and over
Radiotherapy
Proportional hazards model
business.industry
Liver Neoplasms
General Medicine
Middle Aged
medicine.disease
Prognosis
medicine.anatomical_structure
Treatment Outcome
Hepatocellular carcinoma
Lymphatic Metastasis
Cohort
Multivariate Analysis
Regression Analysis
Female
Lymph Nodes
business
Tomography, X-Ray Computed
Follow-Up Studies
Subjects
Details
- ISSN :
- 16993055
- Volume :
- 15
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Clinicaltranslational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
- Accession number :
- edsair.doi.dedup.....947f7c4b92c711229f807cd5be7585ec