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Enoxaparin-induced Wunderlich syndrome in a young patient with anti-GAD 65-associated opsoclonus and limbic encephalitis: a rare complication in a rare disease
- Source :
- BMJ case reports. 14(10)
- Publication Year :
- 2023
-
Abstract
- Wunderlich syndrome is a rare condition characterised by acute spontaneous non-traumatic renal haemorrhage into the subcapsular and perirenal spaces. Our case of anti-GAD65-associated autoimmune encephalitis (AE), aged 30 years, developed this complication following use of enoxaparin and was managed by selective glue embolisation of subsegmental branches of right renal cortical arteries. Our case had opsoclonus as one of the clinical manifestations, which has till now been described in only two patients of this AE. This patient received all forms of induction therapies (steroids, plasmapheresis, intravenous immunoglobulin and rituximab) following which she had good improvement in her clinical condition. The good response to immunotherapy is also a point of discussion as this has been rarely associated with anti-GAD65 AE.
- Subjects :
- Autoimmune encephalitis
medicine.medical_specialty
business.industry
medicine.medical_treatment
Limbic encephalitis
General Medicine
Opsoclonus
medicine.disease
Surgery
Ocular Motility Disorders
Rare Diseases
Wunderlich syndrome
Limbic Encephalitis
medicine
Encephalitis
Humans
Plasmapheresis
Rituximab
Female
Enoxaparin
business
medicine.drug
Rare disease
Subjects
Details
- ISSN :
- 1757790X
- Volume :
- 14
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- BMJ case reports
- Accession number :
- edsair.doi.dedup.....949a751ffdeedb246d0f0858f28d08c6