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Mitochondrial Donation — Which Women Could Benefit?
- Source :
- New England Journal of Medicine. 380:1971-1972
- Publication Year :
- 2019
- Publisher :
- Massachusetts Medical Society, 2019.
-
Abstract
- Predicting the Risk of Mitochondrial Disease The risk of having a child affected with mitochondrial disease can be predicted, albeit within the limits of substantial variability, according to the proportion of mutant mitochondrial genomes carried by the mother.
- Subjects :
- Mitochondrial Diseases
Mitochondrial replacement therapy
Mitochondrial disease
Mutant
030204 cardiovascular system & hematology
DNA, Mitochondrial
Genome
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Humans
Medicine
Genetic Testing
030212 general & internal medicine
Child
Genetic testing
Genetics
medicine.diagnostic_test
business.industry
Bayes Theorem
General Medicine
medicine.disease
Mitochondrial Replacement Therapy
chemistry
Donation
Mutation
Mutation (genetic algorithm)
Female
business
DNA
Subjects
Details
- ISSN :
- 15334406 and 00284793
- Volume :
- 380
- Database :
- OpenAIRE
- Journal :
- New England Journal of Medicine
- Accession number :
- edsair.doi.dedup.....94ac2c1a89e89a5a23c94d498a2ae93d
- Full Text :
- https://doi.org/10.1056/nejmc1808565