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Immunological changes in peripheral blood following nasal allergen challenge in subjects with allergic rhinitis pre‐ and post‐peptide immunotherapy: An open‐label clinical study
- Source :
- Allergy. 76:1907-1911
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- We investigated immunological changes in peripheral blood samples obtained from individuals with allergic rhinitis (AR), triggered by exposure to cat allergen, who were receiving peptide immunotherapy. Ten cat-sensitized AR individuals received cat peptide antigen desensitization (Cat-PAD, Circassia Pharmaceuticals PLC, Oxford, UK)1 , an experimental peptide immunotherapy for AR; participants were treated with four intradermal injections (at 4-week intervals) of 6 nmol Cat-PAD.
- Subjects :
- 0301 basic medicine
Nasal Provocation Tests
medicine.medical_treatment
Immunology
Peptide
Allergen challenge
Clinical study
03 medical and health sciences
0302 clinical medicine
Humans
Immunology and Allergy
Medicine
Pre and post
Desensitization (medicine)
chemistry.chemical_classification
business.industry
Immunotherapy
Allergens
Rhinitis, Allergic
Peripheral blood
Nasal Mucosa
030104 developmental biology
030228 respiratory system
chemistry
Open label
Peptides
business
Subjects
Details
- ISSN :
- 13989995 and 01054538
- Volume :
- 76
- Database :
- OpenAIRE
- Journal :
- Allergy
- Accession number :
- edsair.doi.dedup.....955eb1e73d5ad198da4d30d5a36d2606