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Long-Term Resveratrol Supplementation as a Secondary Prophylaxis for Stroke
- Source :
- Oxidative Medicine and Cellular Longevity, Vol 2018 (2018), Oxidative Medicine and Cellular Longevity
- Publication Year :
- 2018
- Publisher :
- Hindawi Limited, 2018.
-
Abstract
- Stroke is a leading cause of mortality worldwide, as well as a source of long-term disabilities and huge socioeconomic costs. This study investigates the effects of resveratrol, an antioxidant supplement, on blood pressure, weight status, glucose, and lipid profile in patients who had a stroke in the last 12 months. Two hundred and twenty-eight patients were divided into three groups: group I received only allopathic treatment (control group), while groups II and III received allopathic treatment with a daily supplementation of oral resveratrol (100 and 200 mg, resp.) for 12 months. In all groups, the changes of the studied parameters were monitored at 6 and 12 months from the initial evaluation. In groups II and III, resveratrol induced significant changes (p<0.05) in the blood pressure, body mass index, as well as all parameters of the lipid profile, and glucose (in nondiabetic patients), compared to the control group. The supplementation of the allopathic treatment with resveratrol had a beneficial effect on all monitored parameters, which serve as major risk factors for stroke.
- Subjects :
- Male
0301 basic medicine
Aging
medicine.medical_specialty
Antioxidant
Article Subject
medicine.medical_treatment
030204 cardiovascular system & hematology
Resveratrol
Biochemistry
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Internal medicine
Stilbenes
medicine
Humans
In patient
lcsh:QH573-671
Stroke
medicine.diagnostic_test
business.industry
lcsh:Cytology
Anti-Inflammatory Agents, Non-Steroidal
Secondary prophylaxis
Cell Biology
General Medicine
medicine.disease
030104 developmental biology
Blood pressure
chemistry
Dietary Supplements
Female
business
Lipid profile
Body mass index
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 19420994 and 19420900
- Volume :
- 2018
- Database :
- OpenAIRE
- Journal :
- Oxidative Medicine and Cellular Longevity
- Accession number :
- edsair.doi.dedup.....956771acb17040639bacf3cd11445bc5