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A novel peptide synthesis using fluorous chemistry

Authors :
Tsuyoshi Miura
Kohtaro Goto
Mamoru Mizuno
Daisuke Hosaka
Toshiyuki Inazu
Source :
Chemical Communications. :972-973
Publication Year :
2003
Publisher :
Royal Society of Chemistry (RSC), 2003.

Abstract

Three new fluorous supports for peptide synthesis, i.e., the trialkoxybenzhydryl-type (6), the Wang-type (7) and the tert-butyl-type support (8), were prepared. A bioactive peptide TRH was easily synthesized by an Fmoc strategy using the benzhydryl-type fluorous support with fluorous chemistry.

Details

ISSN :
1364548X and 13597345
Database :
OpenAIRE
Journal :
Chemical Communications
Accession number :
edsair.doi.dedup.....95ea76b59a5d280150d72af64f28adbf