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A Call to Action by the Italian Mesotherapy Society on Scientific Research
- Source :
- Drug Design, Development and Therapy, Drug Design, Development and Therapy, Vol Volume 15, Pp 3041-3047 (2021)
- Publication Year :
- 2021
- Publisher :
- Dove, 2021.
-
Abstract
- Mesotherapy (local intradermal therapy, LIT) is a technique used to slowly spread drugs in tissues underlying the site of injection to prolong the pharmacological effect with respect to intramuscular injection. Recommendations for proper medical use of this technique have been made for pain medicine and rehabilitation, chronic venous disease, sport medicine, musculoskeletal disorders, several dermatological conditions, skin ageing, and immune-prophylaxis. Although mesotherapy is considered a valid technique, unresolved questions remain, which should be answered to standardize methodology and dosing regimen as well as to define the right indications in clinical practice. New randomized controlled trials are needed to test single products (dose, frequency of administration, efficacy and safety). Even infiltration of substances for dermo-cosmetic purposes must be guided by safety and efficacy tests before being proposed by mesotherapy. In this article, we put forth a preclinical and clinical research plan and a health technology assessment as a call to action by doctors, researchers and scientific societies to aid national health authorities in considering mesotherapy for prevention, treatment and rehabilitation paths.<br />Video abstract Point your SmartPhone at the code above. If you have a QR code reader the video abstract will appear. Or use: https://youtu.be/bIuRhGQsUjs
- Subjects :
- medicine.medical_specialty
Technology Assessment, Biomedical
Injections, Intradermal
Pain medicine
medicine.medical_treatment
Pharmaceutical Science
Settore MED/09
RM1-950
Review
law.invention
Randomized controlled trial
law
Drug Discovery
medicine
Humans
Intensive care medicine
intradermal therapy
Randomized Controlled Trials as Topic
Pharmacology
Analgesics
Rehabilitation
business.industry
Health technology
Call to action
Mesotherapy
Clinical research
mesotherapy
Italy
Settore MED/41
research plan
Therapeutics. Pharmacology
Venous disease
business
Societies
Subjects
Details
- Language :
- English
- ISSN :
- 11778881
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Drug Design, Development and Therapy
- Accession number :
- edsair.doi.dedup.....95fa5173bd997c717436b5a11abae10e