Back to Search Start Over

Encapsulation of haloalkane 1-(3-chlorophenyl)-4-(3-chloropropyl)-piperazinium in symmetrical α,α',δ,δ'-tetramethyl-cucurbit[6]uril

Authors :
Cheng-Long Shan
Qian-Jiang Zhu
Xin Xiao
Zhu Tao
Jing-Xin Liu
Zhong-Zheng Gao
Sai-Feng Xue
Source :
Physical chemistry chemical physics : PCCP. 17(14)
Publication Year :
2015

Abstract

Complexation of haloalkane 1-(3-chlorophenyl)-4-(3-chloropropyl)-piperazinium (PZ(+)) dihydrochloride with symmetrical α,α',δ,δ'-tetramethyl-cucurbit[6]uril (TMeQ[6]) has been investigated using NMR spectroscopy, MALDI-TOF mass spectrometry, isothermal titration calorimetry (ITC), and X-ray crystallography. Our data indicate that the chloropropyl group of PZ(+) resides within the cavity of TMeQ[6] in both aqueous solution and the solid state, generating a highly stable inclusion complex PZ(+)@TMeQ[6]. In aqueous solution, the formation of the inclusion complex PZ(+)@TMeQ[6] benefits from the ion-dipole interactions between the guest PZ(+) and the host TMeQ[6]. While in the solid state, hydrogen-bonding interactions also play an important role in stabilizing the inclusion complex PZ(+)@TMeQ[6].

Details

ISSN :
14639084
Volume :
17
Issue :
14
Database :
OpenAIRE
Journal :
Physical chemistry chemical physics : PCCP
Accession number :
edsair.doi.dedup.....9601c7e5f402e268d82240bf0b1423a9