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Supplementary Figure 4 from Potent Anti-leukemia Activities of Chimeric Antigen Receptor–Modified T Cells against CD19 in Chinese Patients with Relapsed/Refractory Acute Lymphocytic Leukemia

Authors :
He Huang
Lei Xiao
Zhen Cai
Hao Zhang
Aiyun Jin
Jinping Wang
Jifang Tu
Wanmao Ni
Yamin Tan
Jue Xie
Jing Jiang
Jie Sun
Qu Cui
Guoqing Wei
Zuyu Liang
Chengfei Pu
Jian Yu
Jimin Shi
Yi Luo
Zhao Wu
Yongxian Hu
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Comparison of CART19 levels in different groups. A, Levels of CART19 cells in PB were shown as assessed by means of qPCR assay at serial time points before and after infusion of CART19 respectively. B, CAR DNA copies in BM and PB on day 7 to 9 after CART19 infusion were compared. CAR DNA copies in BM (Patient 2, 6, 11, 13) were higher than in PB. C, Paired measurements of CAR DNA copies in BM and PB on day 7 to 9 after CART19 infusion, percentage of leukemia cells after FC chemotherapy shows strong correlations (CAR DNA copies in BM VS in PB, Spearman r=0.956, p

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....9668fd556802c1bdaadb63e9eda59006