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Current trends and future perspectives of nanomedicine for the management of colon cancer
- Source :
- European journal of pharmacology. 910
- Publication Year :
- 2021
-
Abstract
- Colon cancer (CC) kills countless people every year throughout the globe. It persists as one of the highly lethal diseases to be treated because the overall survival rate for CC is meagre. Early diagnosis and efficient treatments are two of the biggest hurdles in the fight against cancer. In the present work, we will review thriving strategies for CC targeted drug delivery and critically explain the most recent progressions on emerging novel nanotechnology-based drug delivery systems. Nanotechnology-based animal and human clinical trial studies targeting CC are discussed. Advancements in nanotechnology-based drug delivery systems intended to enhance cellular uptake, improved pharmacokinetics and effectiveness of anticancer drugs have facilitated the powerful targeting of specific agents for CC therapy. This review provides insight into current progress and future opportunities for nanomedicines as potential curative targets for CC treatment. This information could be used as a platform for the future expansion of multi-functional nano constructs for CC's advanced detection and functional drug delivery.
- Subjects :
- Pharmacology
medicine.medical_specialty
Clinical Trials as Topic
business.industry
Colorectal cancer
Cancer
Antineoplastic Agents
medicine.disease
Xenograft Model Antitumor Assays
Clinical trial
Disease Models, Animal
Nanomedicine
Targeted drug delivery
Cell Line, Tumor
Drug delivery
Colonic Neoplasms
medicine
Overall survival
Animals
Humans
business
Intensive care medicine
Nanoparticle Drug Delivery System
Subjects
Details
- ISSN :
- 18790712
- Volume :
- 910
- Database :
- OpenAIRE
- Journal :
- European journal of pharmacology
- Accession number :
- edsair.doi.dedup.....96a1356cd829610f8d550bbc26bca31a