Utilisation des plasmas de référence pour l'estimation de la précision des mesures des dosages radioimmunologiques

This article presents a method for estimating the variability of measurements in radio-immunoassays. Repeated assays are carried out on the same plasma used as a reference. The variances of repeatability (or intraassay) and reproducibility are calculated from the values obtained from the reference. These variances are used to calculate the agreement between two or more values obtained from unknown plasma. Analysis of the values of the plasma reference completes information obtained from standard curves.