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Dried Fruit of the Luffa Sponge as a Source of Chitin for Applications as Skin Substitutes
- Source :
- BioMed Research International, Vol 2014 (2014), BioMed Research International
- Publication Year :
- 2014
- Publisher :
- Hindawi Publishing Corporation, 2014.
-
Abstract
- LUFFACHITINobtained from the residue of the sponge-like dried fruit ofLuffa aegyptiacawas developed as a weavable skin substitute in this study. A chemical analysis revealed thatLUFFACHITINwas composed of a copolymer containing N-acetyl-glucosamine (~40%) as a major monomer with a filamentary structure as demonstrated by both optical and scanning electron microscopy. The pulp-like white residue of the sponge-like dried fruit ofLuffa aegyptiacaafter treatment was then woven into a thin, porous membrane by filtration and lyophilization as a skin substitute for conducting wound-healing study on rats. The results indicated that theLUFFACHITINmembrane showed significant wound-healing enhancement (25 days to complete healing) compared to cotton gauze (>30 days), but not inferior to that ofSACCHACHITIN. Furthermore, theLUFFACHITINmembrane had advantages of having a high yield, better physical properties for fabrication, and a more attractive appearance.
- Subjects :
- Dried fruit
Article Subject
Scanning electron microscope
lcsh:Medicine
Chitin
Gas Chromatography-Mass Spectrometry
General Biochemistry, Genetics and Molecular Biology
chemistry.chemical_compound
Residue (chemistry)
Botany
Animals
Chromatography, High Pressure Liquid
Skin, Artificial
Wound Healing
Chromatography
General Immunology and Microbiology
biology
lcsh:R
General Medicine
biology.organism_classification
Luffa aegyptiaca
Rats
Sponge
Membrane
Monomer
chemistry
Fruit
Chromatography, Thin Layer
Luffa
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 23146133
- Database :
- OpenAIRE
- Journal :
- BioMed Research International
- Accession number :
- edsair.doi.dedup.....96ff93a3e432ebedbe0a754538f353e8
- Full Text :
- https://doi.org/10.1155/2014/458287