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How the devil facial tumor disease escapes host immune responses

Authors :
James C. Kaufman
Hannah V. Siddle
Source :
Oncoimmunology
Publication Year :
2013
Publisher :
Landes Bioscience, 2013.

Abstract

The devil facial tumor disease (DFTD) is a contagious cancer that has recently emerged among Tasmanian devils, rapidly decimating the population. We have recently discovered that DFTD cells lose the expression MHC molecules on the cell surface, explaining how this tumor avoids recognition by host CD8+ T cells.

Details

Language :
English
ISSN :
2162402X and 21624011
Volume :
2
Issue :
8
Database :
OpenAIRE
Journal :
Oncoimmunology
Accession number :
edsair.doi.dedup.....973104933e49ccbb055102197ca13117