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How the devil facial tumor disease escapes host immune responses
- Source :
- Oncoimmunology
- Publication Year :
- 2013
- Publisher :
- Landes Bioscience, 2013.
-
Abstract
- The devil facial tumor disease (DFTD) is a contagious cancer that has recently emerged among Tasmanian devils, rapidly decimating the population. We have recently discovered that DFTD cells lose the expression MHC molecules on the cell surface, explaining how this tumor avoids recognition by host CD8+ T cells.
- Subjects :
- contagious cancer
Immunology
Population
CTVT
Disease
DFTD
Biology
Major histocompatibility complex
Immune system
Interferon
Tasmanian devil
medicine
Immunology and Allergy
education
Author's View
education.field_of_study
epigenetics
extinction
conservation
Cancer
transmissible tumor
interferon
medicine.disease
Oncology
biology.protein
MHC
CD8
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 2162402X and 21624011
- Volume :
- 2
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Oncoimmunology
- Accession number :
- edsair.doi.dedup.....973104933e49ccbb055102197ca13117