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Impact of neutrophil-to-lymphocyte ratio on periprocedural myocardial infarction in patients undergoing non-urgent percutaneous coronary revascularisation
- Source :
- Netherlands Heart Journal
- Publisher :
- Springer Nature
-
Abstract
- Background Pro-thrombotic conditions importantly influence myocardial perfusion and procedural results after percutaneous coronary intervention (PCI). The neutrophil-to-lymphocyte ratio (NLR) has emerged as a predictor of cardiovascular events and of long-term prognosis, especially in ST-elevation myocardial infarction patients undergoing primary PCI. The aim of our study was to evaluate the role of NLR on periprocedural myocardial infarction (MI) in patients undergoing non-urgent PCI. Methods In a consecutive cohort of 1542 patients undergoing PCI, myonecrosis biomarkers were determined at 6, 12, 24 and 48 hours post-procedure. Patients were divided into quintiles according to NLR values. Periprocedural myonecrosis was defined as a troponin I increase of 3 times the upper limit of normal or as 50 % of an elevated baseline value, whereas periprocedural MI was defined as a CK-MB increase of 3 times the upper limit of normal or 50 % of baseline. Results Higher NLR was related to age, established risk factors and cardiovascular history. NLR was associated with severe coronary artery disease (p = 0.009), tighter stenosis (p
- Subjects :
- medicine.medical_specialty
Original Article - E‑Learning
medicine.medical_treatment
Periprocedural myocardial infarction
030204 cardiovascular system & hematology
Coronary artery disease
03 medical and health sciences
0302 clinical medicine
Restenosis
Internal medicine
medicine
030212 general & internal medicine
Myocardial infarction
Neutrophil to lymphocyte ratio
business.industry
Stent
Percutaneous coronary intervention
PCI
medicine.disease
Neutrophil/lymphocyte ratio
Conventional PCI
Cardiology
White blood cells
business
Cardiology and Cardiovascular Medicine
TIMI
Subjects
Details
- Language :
- English
- ISSN :
- 15685888
- Volume :
- 24
- Issue :
- 7-8
- Database :
- OpenAIRE
- Journal :
- Netherlands Heart Journal
- Accession number :
- edsair.doi.dedup.....9819db9a13783fd1dc9b74b9ca382ef8
- Full Text :
- https://doi.org/10.1007/s12471-016-0850-6