Molecular Characterization of Autochthonous Chikungunya Cluster in Latium Region, Italy

Authors :: Paola Scognamiglio
Eleonora Lalle
Domenico Di Lallo
Licia Bordi
Silvia Meschi
Antonino Di Caro
Fabrizio Carletti
Emanuele Nicastri
Concetta Castilletti
Francesco Vairo
Giuseppe Ippolito
Maria Rosaria Capobianchi
Vincenzo Panella
Francesca Colavita
Source :: Emerging Infectious Diseases, Emerging Infectious Diseases, Vol 24, Iss 1, Pp 178-180 (2018)
Publication Year :: 2018
Publisher :: Centers for Disease Control and Prevention, 2018.
Abstract: We report partial molecular characterization of isolates from an autochthonous chikungunya virus cluster in the Latium Region of Italy. E1 sequences from 3 patients differ substantially from sequences from the 2007 outbreak in Italy and lack the A226V substitution associated with increased viral fitness in the Aedes albopictus mosquito vector.

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