Back to Search
Start Over
Impact of the COVID-19 pandemic and post-epidemic periods on the process of endovascular treatment for acute anterior circulation ischaemic stroke
- Source :
- BMC Neurology, BMC Neurology, Vol 21, Iss 1, Pp 1-8 (2021)
- Publication Year :
- 2021
- Publisher :
- BioMed Central, 2021.
-
Abstract
- Background and purpose The purpose of our study was to analyse endovascular treatment (EVT) in patients presenting acute anterior circulation ischemic stroke with large-vessel occlusion (AIS-LVO) during the pandemic and post-epidemic periods. Methods Patients with AIS-LVO of the anterior circulation who underwent EVT were enrolled. According to the times of Wuhan closure and reopening, patients were divided into a pre-pandemic group (from November 8, 2019, to January 22, 2020), pandemic group (from January 23, 2020, to April 8, 2020) and post-epidemic group (from April 9, 2020, to June 24, 2020). The primary endpoints were the time delay among symptom onset to arriving hospital door, to groining puncture and to vascular reperfusion. Secondary endpoints were the functional outcomes evaluated by 90-day modified Rankin scale (mRS) score. Results In total, the times from onset to reperfusion (OTR, median 356 min vs. 310 min, p = 0.041) and onset to door (OTD, median 238 min vs. 167 min, p = 0.017) were prolonged in the pandemic group compared to the pre-pandemic group, and the delay continue in the post-epidemic period. In the subgroup analysis, the time from door to imaging (DTI) was significantly prolonged during the pandemic period. Interestingly, the prolonged DTI was corrected in the directly admitted subgroup during post-epidemic period. In addition, the functional outcomes showed no significant differences across the three periods. Conclusions Total time and prehospital time were prolonged during the pandemic and post-epidemic periods. Urgent public education and improved in-hospital screening processes are necessary to decrease time delays.
- Subjects :
- Male
medicine.medical_specialty
Neurology
Subgroup analysis
Brain Ischemia
Modified Rankin Scale
Pandemic
Occlusion
Humans
Medicine
Neurochemistry
Endovascular treatment
RC346-429
Aged
Ischemic Stroke
Retrospective Studies
Aged, 80 and over
business.industry
Research
Endovascular Procedures
COVID-19
Retrospective cohort study
General Medicine
Middle Aged
Treatment Outcome
Anesthesia
Acute ischaemic stroke
Reperfusion
Female
Neurology. Diseases of the nervous system
Neurology (clinical)
Neurosurgery
business
Post-epidemic
Subjects
Details
- Language :
- English
- ISSN :
- 14712377
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- BMC Neurology
- Accession number :
- edsair.doi.dedup.....9860d3344026f56aa369a531a6ce5c1f