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Thoroughbred Horse Single Nucleotide Polymorphism and Expression Database: HSDB
- Source :
- Asian-Australasian Journal of Animal Sciences, Vol 27, Iss 9, Pp 1236-1243 (2014), Asian-Australasian Journal of Animal Sciences, ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES(27): 9
- Publication Year :
- 2014
- Publisher :
- Asian-Australasian Association of Animal Production Societies, 2014.
-
Abstract
- Genetics is important for breeding and selection of horses but there is a lack of well-established horse-related browsers or databases. In order to better understand horses, more variants and other integrated information are needed. Thus, we construct a horse genomic variants database including expression and other information. Horse Single Nucleotide Polymorphism and Expression Database (HSDB) (http://snugenome2.snu.ac.kr/HSDB) provides the number of unexplored genomic variants still remaining to be identified in the horse genome including rare variants by using population genome sequences of eighteen horses and RNA-seq of four horses. The identified single nucleotide polymorphisms (SNPs) were confirmed by comparing them with SNP chip data and variants of RNA-seq, which showed a concordance level of 99.02% and 96.6%, respectively. Moreover, the database provides the genomic variants with their corresponding transcriptional profiles from the same individuals to help understand the functional aspects of these variants. The database will contribute to genetic improvement and breeding strategies of Thoroughbreds.
- Subjects :
- Concordance
Population
lcsh:Animal biochemistry
Single-nucleotide polymorphism
Expression
Biology
computer.software_genre
Horse
Genome
Article
Database
education
lcsh:QP501-801
Selection (genetic algorithm)
Thoroughbred horse
lcsh:SF1-1100
Thoroughbred
Variants
Genetics
education.field_of_study
SNP genotyping
Horse genome
Animal Science and Zoology
lcsh:Animal culture
computer
Food Science
Subjects
Details
- Language :
- English
- ISSN :
- 19765517 and 10112367
- Volume :
- 27
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Asian-Australasian Journal of Animal Sciences
- Accession number :
- edsair.doi.dedup.....986bad522860ae93956cf90830162d7e