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In addition to mTOR and JAK/STAT, NLRP3 inflammasome is another key pathway activated in sarcoidosis
- Source :
- European Respiratory Journal, European Respiratory Journal, European Respiratory Society, 2020, 55 (3), pp.2000149. ⟨10.1183/13993003.00149-2020⟩
- Publication Year :
- 2020
- Publisher :
- HAL CCSD, 2020.
-
Abstract
- International audience; The study of Huppertz and co-workers addresses the role of the NLRP3 inflammasome in sarcoidosis. Employing both mouse model and human samples, they provide evidence of NLPR3 inflammasome activation and increased IL-1β production in lung granulomas. http://bit.ly/32a4GsI Cite this article as: Riteau N, Bernaudin J-F. In addition to mTOR and JAK/STAT, NLRP3 inflammasome is another key pathway activated in sarcoidosis.
- Subjects :
- Pulmonary and Respiratory Medicine
Granuloma
Sarcoidosis
integumentary system
business.industry
Inflammasomes
TOR Serine-Threonine Kinases
[SDV]Life Sciences [q-bio]
JAK-STAT signaling pathway
Inflammasome
medicine.disease
3. Good health
03 medical and health sciences
0302 clinical medicine
030228 respiratory system
NLR Family, Pyrin Domain-Containing 3 Protein
Cancer research
Medicine
Humans
030212 general & internal medicine
business
PI3K/AKT/mTOR pathway
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 09031936 and 13993003
- Database :
- OpenAIRE
- Journal :
- European Respiratory Journal, European Respiratory Journal, European Respiratory Society, 2020, 55 (3), pp.2000149. ⟨10.1183/13993003.00149-2020⟩
- Accession number :
- edsair.doi.dedup.....988092f1bc30cdefd6c13f7b598e663f