Back to Search
Start Over
Hepatitis Delta Virus Infection and Labrea Hepatitis
- Source :
- JAMA. 258:479
- Publication Year :
- 1987
- Publisher :
- American Medical Association (AMA), 1987.
-
Abstract
- To define more exactly the epidemiology of delta virus infection and confirm its role in causing fulminant Labrea hepatitis in the Amazon Basin, we studied the prevalence of delta virus infection among persons with acute and chronic hepatitis B virus infection in the Boca do Acre district of the southern Amazon Basin. Delta virus infection was found in 24% of asymptomatic hepatitis B virus carriers, 29% of acute nonfulminant hepatitis B cases, 74% of fulminant hepatitis B cases, and 100% of chronic hepatitis B cases. Chronic delta virus infection occurred primarily in older children and adults, while acute and fulminant delta virus infection occurred in young children as well. In fulminant hepatitis cases, delta virus superinfection of hepatitis B virus carriers was the most common serological pattern; histopathologic examination showed features identical to those described in fulminant hepatitis cases of similar etiology in Colombia and Venezuela. Delta virus infection is highly endemic in the southern Amazon Basin and is the principal cause of Labrea hepatitis. ( JAMA 1987;258:479-483)
- Subjects :
- Adult
Male
Adolescent
viruses
Fulminant
medicine.disease_cause
Virus
Hepatitis B Antigens
medicine
Humans
Longitudinal Studies
Hepatitis B Antibodies
Child
Fulminant hepatitis
Hepatitis delta Antigens
Hepatitis
Hepatitis B virus
business.industry
Infant
General Medicine
Middle Aged
Hepatitis B
medicine.disease
Virology
Hepatitis D
Child, Preschool
Superinfection
Acute Disease
Chronic Disease
Immunology
Female
business
Brazil
geographic locations
Subjects
Details
- ISSN :
- 00987484
- Volume :
- 258
- Database :
- OpenAIRE
- Journal :
- JAMA
- Accession number :
- edsair.doi.dedup.....988c1f51961a621458fb80b228089889
- Full Text :
- https://doi.org/10.1001/jama.1987.03400040077025