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The safety of influenza vaccines in children: An Institute for Vaccine Safety white paper
- Source :
- Vaccine. :F1-F67
- Publisher :
- Published by Elsevier Ltd.
-
Abstract
- Most influenza vaccines are generally safe, but influenza vaccines can cause rare serious adverse events. Some adverse events, such as fever and febrile seizures, are more common in children than adults. There can be differences in the safety of vaccines in different populations due to underlying differences in genetic predisposition to the adverse event. Live attenuated vaccines have not been studied adequately in children under 2 years of age to determine the risks of adverse events; more studies are needed to address this and several other priority safety issues with all influenza vaccines in children. All vaccines intended for use in children require safety testing in the target age group, especially in young children. Safety of one influenza vaccine in children should not be extrapolated to assumed safety of all influenza vaccines in children. The low rates of adverse events from influenza vaccines should not be a deterrent to the use of influenza vaccines because of the overwhelming evidence of the burden of disease due to influenza in children.
- Subjects :
- Vaccine safety
Hypersensitivity reactions
Local reactions following IIV
Guillain-Barre syndrome
White paper
Attenuated vaccine
Influenza vaccine
Cellulitis-like reactions
Vaccination
Academies and Institutes
virus diseases
Infectious Diseases
Influenza Vaccines
Child, Preschool
Molecular Medicine
Risk assessment
medicine.medical_specialty
Fever
Febrile seizures
Vaccines, Attenuated
Risk Assessment
Seizures, Febrile
Multiple sclerosis
Immunology and Microbiology(all)
Influenza, Human
Hypersensitivity
medicine
Humans
Bell's palsy
Intensive care medicine
Adverse effect
Narcolepsy
General Veterinary
General Immunology and Microbiology
business.industry
ADEM
Public Health, Environmental and Occupational Health
Infant
Myalgia
medicine.disease
veterinary(all)
Influenza
Consumer Product Safety
Immunology
Inflammatory arthritis
ITP
business
Malaise
Subjects
Details
- Language :
- English
- ISSN :
- 0264410X
- Database :
- OpenAIRE
- Journal :
- Vaccine
- Accession number :
- edsair.doi.dedup.....988e34e4e1dd344a74e48f1122c10698
- Full Text :
- https://doi.org/10.1016/j.vaccine.2015.10.080