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Incident chronic kidney disease: trends in management and outcomes
- Source :
- Clinical Kidney Journal
- Publication Year :
- 2016
- Publisher :
- Oxford University Press, 2016.
-
Abstract
- Background Management trends in early chronic kidney disease (CKD) and their associations with clinical outcomes have not previously been reported. Methods We evaluated incident (Stage G3A) CKD patients from an integrated health care system in 2004–06, 2007–09 and 2010–12 to determine adjusted trends in screening (urinary protein quantification), treatment [prescription for angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB), and statin] and nephrology referral. For the same time periods, adjusted rates for mortality, progression to Stage G4 CKD and hospitalization for myocardial infarction or heart failure were calculated and compared across time periods. Results There were 728, 788 and 956 patients with incident CKD in 2004–06, 2007–09 and 2010–12, respectively. Adjusted rates of proteinuria quantification (31, 39 and 51 screens/100 person-years), statin prescription (53, 63 and 64 prescriptions/100 person-years) and nephrology referral (2, 3 and 5 referrals/100 person-years) all increased over time (P for trend 0.4 in all cases). Conclusion In this integrated health care system, management of incident CKD over the past decade has intensified.
- Subjects :
- Nephrology
medicine.medical_specialty
Treatment outcome
030232 urology & nephrology
renin-angiotensin system
030204 cardiovascular system & hematology
urologic and male genital diseases
03 medical and health sciences
Patient referral
0302 clinical medicine
Internal medicine
Renin–angiotensin system
Epidemiology
Chronic Kidney Disease
medicine
Chronic renal insufficiency
Intensive care medicine
Transplantation
Proteinuria
chronic renal insufficiency
business.industry
cardiovascular
medicine.disease
female genital diseases and pregnancy complications
epidemiology
medicine.symptom
proteinuria
business
Kidney disease
Subjects
Details
- Language :
- English
- ISSN :
- 20488513 and 20488505
- Volume :
- 9
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Clinical Kidney Journal
- Accession number :
- edsair.doi.dedup.....990c045610e2fd5e89a3ec7729c34408