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Tetracycline Loaded Collagen/Hydroxyapatite Composite Materials for Biomedical Applications
- Source :
- Journal of Nanomaterials, Vol 2015 (2015)
- Publication Year :
- 2015
- Publisher :
- Hindawi Limited, 2015.
-
Abstract
- The paper describes the preparation, characterisation, and testing of tetracycline loaded collagen-carboxymethylcellulose/hydroxyapatite ternary composite materials. The synthesis of this drug delivery system consists in two steps: the first step is the mineralization of collagen-carboxymethylcellulose gel while the second step corresponds to the loading of the ternary composite material with tetracycline. The obtained DDS is characterised by physicochemical, morphological, and release behaviour by using FTIR spectroscopy and microscopy, scanning electron microscopy, and UV-VIS spectroscopy. Based on the release study, it can be assumed that tetracycline is released in a prolonged way, assuring at least 6 days of antiseptic properties.
- Subjects :
- Materials science
Article Subject
Tetracycline
Scanning electron microscope
Chemical engineering
lcsh:Technology (General)
Drug delivery
Microscopy
medicine
Hydroxyapatite composite
lcsh:T1-995
General Materials Science
Fourier transform infrared spectroscopy
Ternary operation
Spectroscopy
medicine.drug
Subjects
Details
- ISSN :
- 16874129 and 16874110
- Volume :
- 2015
- Database :
- OpenAIRE
- Journal :
- Journal of Nanomaterials
- Accession number :
- edsair.doi.dedup.....9918acc613e70754ab8be892e557710b