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(22E,24S)-24-Propylcholest-5en-3α-acetate: A New Steroid from the Stembark Aglaia angustifolia (Miq.) (Meliaceae)
- Source :
- Molbank, Vol 2020, Iss 1, p M1112 (2020)
- Publication Year :
- 2020
- Publisher :
- MDPI AG, 2020.
-
Abstract
- A new propylcholesterol-type steroid, namely (22E,24S)-24-propylcholest-5en-3α-acetate (1), has been isolated from the stembark of Aglaia angustifolia (Miq.). The structure of 1 was determined on the basis of spectroscopic data including 1D- and 2D-NMR as well as high resolution mass spectroscopy analysis. Compound 1 showed weak activity against the MCF-7 breast cancer cell line.
- Subjects :
- aglaia angustifolia
Meliaceae
biology
010405 organic chemistry
Stereochemistry
Chemistry
medicine.medical_treatment
Organic Chemistry
High resolution
meliaceae
biology.organism_classification
01 natural sciences
Biochemistry
mcf-7
lcsh:QD146-197
0104 chemical sciences
Steroid
010404 medicinal & biomolecular chemistry
Breast cancer cell line
MCF-7
Aglaia angustifolia
medicine
lcsh:Inorganic chemistry
propylcholesterol
Physical and Theoretical Chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 14228599
- Volume :
- 2020
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Molbank
- Accession number :
- edsair.doi.dedup.....9935ca83b3c16b5a8df91eac0b16b396