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Antifertility Activity ofQuassia amara: Quassin Inhibits the Steroidogenesis in Rat Leydig CellsIn Vitro
- Source :
- Planta Medica. 61:180-182
- Publication Year :
- 1995
- Publisher :
- Georg Thieme Verlag KG, 1995.
-
Abstract
- The crude methanol extract of the stem wood of Quassia amara L. inhibited both the basal and LH-stimulated testosterone secretion of rat Leydig cells in a dose-dependent fashion. Fractionation of the extract by chromatography gave quassin (1) and 2-methoxycanthin-6-one (2); compound 1 proved to be the bioactive agent.
- Subjects :
- Male
medicine.medical_specialty
Glaucarubin
Pharmaceutical Science
Biology
Pharmacognosy
Pharmacology
Analytical Chemistry
chemistry.chemical_compound
Internal medicine
Drug Discovery
medicine
Animals
Quassia amara
Testosterone
Rats, Wistar
Cells, Cultured
Plants, Medicinal
Quassins
Leydig cell
Organic Chemistry
Leydig Cells
Biological activity
biology.organism_classification
In vitro
Rats
Fertility
medicine.anatomical_structure
Endocrinology
Complementary and alternative medicine
chemistry
Quassia
Molecular Medicine
Quassin
Subjects
Details
- ISSN :
- 14390221 and 00320943
- Volume :
- 61
- Database :
- OpenAIRE
- Journal :
- Planta Medica
- Accession number :
- edsair.doi.dedup.....995f51a5eec37237c1e56bb2d4aee635
- Full Text :
- https://doi.org/10.1055/s-2006-958044