A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease

Authors :: Bingwen Eugene Fan
Chong Chern Hao
Veeraraghavan Meyyur Aravamudan
Navin Kuthah
Nicholas Wong Wai Cheong
Emily En-Xian Tan
Ikram Hussain
Chaozer Er
Source :: Case Reports in Medicine, Vol 2018 (2018), Case Reports in Medicine
Publication Year :: 2018
Publisher :: Hindawi Limited, 2018.
Abstract: Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without the need of etoposide. Based on our literature search, this is the first case of parvovirus related HLH in a patient with HbH disease in the medical literature.

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