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Using informatics and mobile health to improve medication safety monitoring in kidney transplant recipients
- Source :
- American Journal of Health-System Pharmacy. 76:1143-1149
- Publication Year :
- 2019
- Publisher :
- Oxford University Press (OUP), 2019.
-
Abstract
- Purpose The development, testing, and preliminary validation of a technology-enabled, pharmacist-led intervention aimed at improving medication safety and outcomes in kidney transplant recipients are described. Summary Medication safety issues, encompassing medication errors (MEs), medication nonadherence, and adverse drug events (ADEs), are a predominant cause of poor outcomes after kidney transplantation. However, a limited number of clinical trials assessing the effectiveness of technology in improving medication safety and outcomes in transplant recipients have been conducted. Through an iterative, evidence-based approach, a technology-enabled intervention aimed at improving posttransplant medication safety outcomes was developed, tested, and preliminarily validated. Early acceptability and feasibility results from a prospective, randomized controlled trial assessing the effectiveness of this system are reported here. Of the 120 patients enrolled into the trial at the time of writing, 60 were randomly assigned to receive the intervention. At a mean ± S.D. follow-up of 5.8 ± 4.0 months, there were 2 patient dropouts in the intervention group, resulting in a retention rate of 98%, which was higher than the expected 90% retention rate. Conclusion The development and deployment of a comprehensive medication safety monitoring dashboard for kidney transplant recipients is feasible and acceptable to patients in the current healthcare environment. An ongoing randomized controlled clinical trial is assessing whether such a system reduces MEs and ADRs, leading to improved patient outcomes.
- Subjects :
- Adult
Evidence-Based Pharmacy Practice
Graft Rejection
Male
medicine.medical_specialty
Pharmacist
030204 cardiovascular system & hematology
Pharmacists
Medication Adherence
law.invention
Young Adult
03 medical and health sciences
Professional Role
0302 clinical medicine
Randomized controlled trial
law
Intervention (counseling)
Health care
Electronic Health Records
Humans
Medication Errors
Medicine
Prospective Studies
030212 general & internal medicine
Program Development
Kidney transplantation
Pharmacology
Internet
business.industry
Health Policy
Graft Survival
Health Plan Implementation
Retention rate
medicine.disease
Kidney Transplantation
Mobile Applications
Telemedicine
Transplant Recipients
Clinical trial
Informatics
Emergency medicine
Female
Smartphone
Drug Monitoring
business
Immunosuppressive Agents
Subjects
Details
- ISSN :
- 15352900 and 10792082
- Volume :
- 76
- Database :
- OpenAIRE
- Journal :
- American Journal of Health-System Pharmacy
- Accession number :
- edsair.doi.dedup.....99e7e5457b189c1a8a3bd7a3b62a835c
- Full Text :
- https://doi.org/10.1093/ajhp/zxz115