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Neural substrates involved in anger induced by audio-visual film clips among patients with alcohol dependency

Authors :
Jin-Hun Sohn
Bae Hwan Lee
Mi-Sook Park
Source :
Journal of Physiological Anthropology(36), Journal of Physiological Anthropology
Publication Year :
2016
Publisher :
Springer Science and Business Media LLC, 2016.

Abstract

Background: Very little is known about the neural circuitry underlying anger processing among alcoholics. The purpose of this study was to examine the altered brain activity of alcoholic individuals during transient anger emotion. Methods: Using functional magnetic resonance imaging (fMRI), 18 male patients diagnosed with alcohol dependence in an inpatient alcohol treatment facility and 16 social drinkers with similar demographics were scanned during the viewing of anger-provoking film clips. Results: While there was no significant difference in the level of experienced anger between alcohol-dependent patients and non-alcoholic controls, significantly greater activation was observed in the bilateral dorsal anterior cingulate cortex (dACC) and the right precentral gyrus among alcoholic patients compared to the normal controls. Conclusions: In summary, specific brain regions were identified that are associated with anger among patients with alcohol dependency.

Details

ISSN :
18806805
Volume :
36
Database :
OpenAIRE
Journal :
Journal of Physiological Anthropology
Accession number :
edsair.doi.dedup.....9a141fda87d5c773d3fc7bee06054cc1
Full Text :
https://doi.org/10.1186/s40101-016-0102-x