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Visit‑to‑visit blood pressure variability is associated with arterial stiffness in Chinese adults: A prospective analysis
- Source :
- The Journal of Clinical Hypertension
- Publication Year :
- 2021
- Publisher :
- John Wiley and Sons Inc., 2021.
-
Abstract
- Blood pressure (BP) variability may have its effect on the development of vascular disease. The authors aimed to examine the association between the visit‐to‐visit variability (VVV) of BP and arterial stiffness in Chinese adults. The authors included 1407 participants from a prospective cohort study of community residents who were ≥40 years, without a history of myocardial infarction or stroke, and with data at the baseline, the second and the third visits in 2008, 2009, and 2013. The VVV of BP was defined as the standard deviation (SD), the coefficient of variation (CV), the average successive variability (ASV), and the variability independent of the mean (VIM) in BP levels at the 3 visits. Arterial stiffness was measured by brachial‐ankle pulse wave velocity (ba‐PWV) at the 2nd and the 3rd visits. Levels of ba‐PWV change and the occurrence of an elevated ba‐PWV increased significantly in the highest tertile of VVV measures of systolic BP (SBP) and pulse pressure (PP) compared with the lowest tertile, respectively. The multivariable regression analysis revealed that VVV measures of SBP and PP were significantly associated with levels of ba‐PWV change and the risks of developing an elevated ba‐PWV. The odds ratios (ORs) and 95% confidence intervals (CIs) for the risk were 2.12 (1.57–3.12) and 1.92 (1.38–2.68) in participants with the highest versus the lowest tertile of SBP‐SD and PP‐SD, respectively. No significant association was found for diastolic BP variability measures. The increased long‐term variabilities of SBP and PP were associated with an increased risk of arterial stiffness.
- Subjects :
- Adult
medicine.medical_specialty
brachial‐ankle pulse wave velocity
China
Endocrinology, Diabetes and Metabolism
Blood Pressure
030204 cardiovascular system & hematology
Pulse Wave Analysis
03 medical and health sciences
0302 clinical medicine
Vascular Stiffness
Risk Factors
Internal medicine
Internal Medicine
Blood Pressure Variability
Medicine
Humans
Ankle Brachial Index
030212 general & internal medicine
cardiovascular diseases
Prospective Studies
Prospective cohort study
Pulse wave velocity
Stroke
Original Paper
business.industry
Odds ratio
medicine.disease
Prognosis
Confidence interval
Pulse pressure
Blood pressure
arterial stiffness
Hypertension
Arterial stiffness
Cardiology
Commentary
Cardiology and Cardiovascular Medicine
business
circulatory and respiratory physiology
Subjects
Details
- Language :
- English
- ISSN :
- 17517176 and 15246175
- Volume :
- 23
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- The Journal of Clinical Hypertension
- Accession number :
- edsair.doi.dedup.....9a55828e4ddb1facae6cc7d12e58eef7