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Clinical Utility of Highly Purified 10% Liquid Intravenous Immunoglobulin in Kawasaki Disease

Authors :
Manao Nishimura
Yasutaka Nakashima
Hazumu Nagata
Etsuro Nanishi
Takuya Oda
Ken Hatae
Yui Takada
Eiji Kubo
Shouichi Ohga
Source :
The Journal of Pediatrics. 214:227-230
Publication Year :
2019
Publisher :
Elsevier BV, 2019.

Abstract

Compared with a 5% intravenous immunoglobulin, a 10% intravenous immunoglobulin as the first-line treatment of Kawasaki disease significantly reduced the fever duration (10 vs 13 hours, P = .022) among the responders, and the interval to adjunctive therapy for nonresponders (47 vs 49 hours, P = .035). There were no severe adverse events.

Details

ISSN :
00223476
Volume :
214
Database :
OpenAIRE
Journal :
The Journal of Pediatrics
Accession number :
edsair.doi.dedup.....9a85f10146f5864d65a0641f1f7d0b17
Full Text :
https://doi.org/10.1016/j.jpeds.2019.06.018