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Clinical Utility of Highly Purified 10% Liquid Intravenous Immunoglobulin in Kawasaki Disease
- Source :
- The Journal of Pediatrics. 214:227-230
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Compared with a 5% intravenous immunoglobulin, a 10% intravenous immunoglobulin as the first-line treatment of Kawasaki disease significantly reduced the fever duration (10 vs 13 hours, P = .022) among the responders, and the interval to adjunctive therapy for nonresponders (47 vs 49 hours, P = .035). There were no severe adverse events.
- Subjects :
- Male
medicine.medical_specialty
Mucocutaneous Lymph Node Syndrome
Gastroenterology
03 medical and health sciences
0302 clinical medicine
030225 pediatrics
Internal medicine
Humans
Immunologic Factors
Medicine
030212 general & internal medicine
Infusions, Intravenous
Adverse effect
Retrospective Studies
Dose-Response Relationship, Drug
biology
business.industry
Immunoglobulins, Intravenous
medicine.disease
Treatment Outcome
Child, Preschool
Pediatrics, Perinatology and Child Health
Fever duration
biology.protein
Female
Kawasaki disease
Antibody
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 00223476
- Volume :
- 214
- Database :
- OpenAIRE
- Journal :
- The Journal of Pediatrics
- Accession number :
- edsair.doi.dedup.....9a85f10146f5864d65a0641f1f7d0b17
- Full Text :
- https://doi.org/10.1016/j.jpeds.2019.06.018