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Total tumor volume predicts survival following liver resection in patients with hepatocellular carcinoma
- Source :
- Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 37(7)
- Publication Year :
- 2015
-
Abstract
- Assessing the prognosis of patients with hepatocellular carcinoma (HCC) by the number and size of tumors is sometimes difficult. The main purpose of the study was to evaluate the prognostic value of total tumor volume (TTV), which combines the two factors, in patients with HCC who underwent liver resection. We retrospectively reviewed 521 HCC patients from January 2001 to December 2008 in our center. Patients were categorized using the tertiles of TTV. The prognostic value of TTV was assessed. With a median follow-up of 116 months, the 1-, 3-, and 5-year overall survival (OS) rates of the patients were 93.1 , 69.9, and 46.3 %, respectively. OS was significantly differed by TTV tertile groups, and higher TTV was associated with shorter OS (P
- Subjects :
- Male
medicine.medical_specialty
Multivariate analysis
Carcinoma, Hepatocellular
Tumor burden
Milan criteria
Gastroenterology
Resection
03 medical and health sciences
0302 clinical medicine
Internal medicine
Tumor stage
medicine
Hepatectomy
Humans
In patient
Neoplasm Staging
Retrospective Studies
business.industry
Liver Neoplasms
Cancer
General Medicine
Middle Aged
medicine.disease
Prognosis
Surgery
Tumor Burden
Survival Rate
030220 oncology & carcinogenesis
Hepatocellular carcinoma
030211 gastroenterology & hepatology
Female
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 14230380
- Volume :
- 37
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
- Accession number :
- edsair.doi.dedup.....9ad23b5d21fb92d7c842825d888e9c04