Back to Search
Start Over
Eosinophilic hyperplastic lymphogranuloma: Clinical diagnosis and treatment experience of 41 cases
- Source :
- American Journal of Otolaryngology. 38:626-629
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Purpose The purpose of this study was to investigate the clinical features of eosinophilic hyperplastic lymphogranuloma (EHLG) in the head and neck. Materials and methods Collecting the patients who diagnose with EHLG by pathological examination. The EHLG patients with the masses involved regions, such as involved inguinal region, chest wall, abdominal wall, anterior superior iliac spine or clavicle, instead of head and neck were excluding. All of the participants will sign the informed consent form. The history data includes: clinical history, blood routine test, pathological examination, and recurrence will be collected. Results A total of 41 patients of EHLG were included. These patients predominantly presented as an enlarging and painless single or multiple masses with a history of repeated swelling. There were the complaint of itchy skin and pigmentation. The routine blood test showed that the percentage value of eosinophil increased in almost patients including 26 cases had raised absolute eosinophil count. The serum level of lgE was increased in 29 cases remarkably. With the methods of treatments, 36 patients received surgical excision, 3 patients accepted hormonotherapy, and another 2 patients for radiotherapy. The recurrence of EHLG was in 9 patients. Conclusions EHLG is a rare disease. The clinical manifestation (itchy skin and pigmentation) and increased eosinophil play critical values to the diagnosis of EHLG. Confirmed diagnosis always depends on pathological examination. Surgery is a preferred treatment, while low dose of radiotherapy is necessary for preventing relapse after operation and hormonotherapy.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Anterior superior iliac spine
Abdominal wall
Young Adult
03 medical and health sciences
0302 clinical medicine
Eosinophilic
medicine
Humans
Blood test
Child
Angiolymphoid hyperplasia with eosinophilia
Aged
Retrospective Studies
medicine.diagnostic_test
business.industry
Angiolymphoid Hyperplasia with Eosinophilia
Middle Aged
medicine.disease
Combined Modality Therapy
Surgery
Treatment Outcome
medicine.anatomical_structure
Otorhinolaryngology
030220 oncology & carcinogenesis
Female
Histopathology
business
030217 neurology & neurosurgery
Rare disease
Subjects
Details
- ISSN :
- 01960709
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- American Journal of Otolaryngology
- Accession number :
- edsair.doi.dedup.....9b32c660b29fd2b423efa553a4e9144a