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Supplementary Figure 3 from Cyclin E2 Overexpression Is Associated with Endocrine Resistance but not Insensitivity to CDK2 Inhibition in Human Breast Cancer Cells

Authors :
Elizabeth A. Musgrove
Cristin G. Print
Robert L. Sutherland
Rob I. Nicholson
Julia M. Gee
Lance D. Miller
Michael A. Black
Christine S. Lee
Jane Barraclough
Andrew Stone
Marijke N. Boersma
Anita Muthukaruppan
Jian Kang
C. Marcelo Sergio
C. Elizabeth Caldon
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file, 41KB, Supplementary Figure 3: Effect of overexpression of cyclins E1 and E2 on antiestrogen-induced growth arrest. T-47D cells overexpressing cyclin E1, cyclin E2 or vector control were treated with fulvestrant or vehicle. Densitometry of Western blots of cell lysates collected after 24h (A) or 48h (B) fulvestrant treatment. Loading was corrected using β-actin levels. Data represent mean � SEM of quadruplicate experiments.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....9b56fdd7b8ef1692d5996ff085c1d435
Full Text :
https://doi.org/10.1158/1535-7163.22496367