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Progress in Metabonomics of Type 2 Diabetes Mellitus
- Source :
- Molecules, Vol 23, Iss 7, p 1834 (2018), Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
- Publication Year :
- 2018
- Publisher :
- MDPI AG, 2018.
-
Abstract
- With the improvement of living standards and a change in lifestyle, the incidence of type 2 diabetes mellitus (T2DM) is increasing. Its etiology is too complex to be completely understand yet. Metabonomics techniques are used to study the changes of metabolites and metabolic pathways before and after the onset of diabetes and make it more possible to further understand the pathogenesis of T2DM and improve its prediction, early diagnosis, and treatment. In this review, we summarized the metabonomics study of T2DM in recent years and provided a theoretical basis for the study of pathogenesis and the effective prevention and treatment of T2DM.
- Subjects :
- 0301 basic medicine
endocrine system diseases
type 2 diabetes mellitus
Pharmaceutical Science
030209 endocrinology & metabolism
Review
Bioinformatics
Analytical Chemistry
Pathogenesis
lcsh:QD241-441
Islets of Langerhans
03 medical and health sciences
0302 clinical medicine
lcsh:Organic chemistry
Diabetes mellitus
Drug Discovery
Animals
Humans
Metabolomics
Medicine
metabolic pathways
metabonomics
Obesity
Physical and Theoretical Chemistry
business.industry
Incidence (epidemiology)
Organic Chemistry
Type 2 Diabetes Mellitus
nutritional and metabolic diseases
biomarkers
medicine.disease
Oxidative Stress
030104 developmental biology
Diabetes Mellitus, Type 2
Chemistry (miscellaneous)
Metabolome
Etiology
Molecular Medicine
Energy Metabolism
Reactive Oxygen Species
business
Metabolic Networks and Pathways
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 23
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....9b6fb46ceaeafaf07e6cc967a495047c