Suppression of production of mouse 28S ribosomal RNA in mouse-human hybrids segregating mouse chromosomes

Authors :: Orlando J. Miller
Claudio Basilico
Carlo M. Croce
Antonio Talavera
Source :: Proceedings of the National Academy of Sciences of the United States of America. 74(2)
Publication Year :: 1977
Abstract: Mouse-human somatic cell hybrids that lose (segregate) human chromosomes produce only mouse 28S ribosomal RNA even when they retain copies of the human chromosomes that contain the genes for 28S ribosomal RNA. In contrast, mouse-human hybrid cells that segregate mouse chromosomes produce only human 28S ribosomal RNA even when they have retained copies of mouse chromosomes that contain the 28S ribosomal RNA genes.

ISSN :: 00278424
Volume :: 74
Issue :: 2
Database :: OpenAIRE
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Accession number :: edsair.doi.dedup.....9b7d9fd09d0b3baf6774c705cb0378bf

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