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Helicobacter pylori infection and type 1 diabetes mellitus in children
Helicobacter pylori infection and type 1 diabetes mellitus in children
- Source :
- J Diabetes Metab Disord
- Publication Year :
- 2018
-
Abstract
- OBJECTIVES: This study aimed to investigate the association between Helicobacter pylori infection with diabetes mellitus type one and the effect of infected Helicobacter pylori on glycemic control. METHODS: This case control study was conducted on children with and without type 1 diabetes mellitus (T1DM). Demographic data and gastrointestinal symptoms in both groups and glycemic control status and duration of diabetes were recorded in patients with T1DM. Stool test was done on all children to detect Helicobacter pylori antigen. RESULTS: Sixty three children with T1DM with a mean of 10.88 ± 2.84 years and 105 control children with an average age 10.17 ± 2.55 years (P = 0/09) were involved in this study. The frequency of Helicobacter pylori infection in patients with T1DM was 17/63 (27%) and 25/105 (23.8%) in control group, (P = 0/64). The frequency of bloating, epigastric pain and nausea was not significantly different between the two groups. The frequency of epigastric pain in children with diabetes with helicobacter infection was significantly higher than non-infected children with diabetes (29.4% vs. 2.2%) (P = 0.004).The mean duration of diabetes (P = 0.53), age diagnosis of diabetes (P = 0.09), fasting blood glucose (P = 0.18), glycosylated hemoglobin (P = 0.08) and the daily insulin dose (P = 0.18) in patients with T1DM with and without helicobacter pylori infection had not significantly different. CONCLUSIONS: There was no significant association between Helicobacter pylori infection and diabetes in children 5–15 years old, and glycemic control status was not difference in patients with T1DM with and without Helicobacter pylori infection.
- Subjects :
- medicine.medical_specialty
Nausea
Endocrinology, Diabetes and Metabolism
030209 endocrinology & metabolism
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Internal medicine
Diabetes mellitus
Internal Medicine
medicine
030212 general & internal medicine
Helicobacter
Glycemic
Type 1 diabetes
medicine.diagnostic_test
biology
Stool test
business.industry
Case-control study
Helicobacter pylori
biology.organism_classification
medicine.disease
medicine.symptom
business
Research Article
Subjects
Details
- ISSN :
- 22516581
- Volume :
- 19
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of diabetes and metabolic disorders
- Accession number :
- edsair.doi.dedup.....9bc76d33fe799b553b7f210d197a0156