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<scp>CAR‐T</scp> cell therapy targeting B cell maturation antigen is effective for relapsed/refractory multiple myeloma, including cases with poor performance status

Authors :
Juan Du
Runhong Wei
Songfu Jiang
Hua Jiang
Lu Li
Wanting Qiang
Haiyan He
Lin Shi
Qiuling Ma
Kang Yu
Xiaoyuan Zhang
Hanyi Ding
Xuedong Sun
Fang Xiang
Lin Zhu
Zhi Cheng
Weijun Fu
Source :
American Journal of Hematology. 97:933-941
Publication Year :
2022
Publisher :
Wiley, 2022.

Abstract

In this open-label, single-arm, phase I/II clinical trial, we evaluated the efficacy of anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR)-T cell (HDS269B) therapy in 49 relapsed/refractory multiple myeloma (RRMM) patients, including 20 with Eastern Cooperative Oncology Group (ECOG) grade 3-4. After HDS269B infusion (9 &#215; 10

Details

ISSN :
10968652 and 03618609
Volume :
97
Database :
OpenAIRE
Journal :
American Journal of Hematology
Accession number :
edsair.doi.dedup.....9bfe83e1e2988e7907d8614c40c79a7b