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Polyhydroxylated steroidal glycosides from Paris polyphylla
- Source :
- Journal of natural products. 75(6)
- Publication Year :
- 2012
-
Abstract
- Three new steroidal saponins, parisyunnanosides G-I (1-3), one new C(21) steroidal glycoside, parisyunnanoside J (4), and three known compounds, padelaoside B (5), pinnatasterone (6), and 20-hydroxyecdyson (7), were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Compounds 1 and 3 have unique trisdesmoside structures that include a C-21 β-d-galactopyranose moiety. All compounds were evaluated for their cytotoxicity against human CCRF leukemia cells.
- Subjects :
- Steroidal glycosides
Stereochemistry
Pharmaceutical Science
Analytical Chemistry
Drug Discovery
Liliaceae
Moiety
Humans
Cytotoxicity
Pharmacology
chemistry.chemical_classification
biology
Molecular Structure
Organic Chemistry
Paris polyphylla
Glycoside
Saponins
biology.organism_classification
Antineoplastic Agents, Phytogenic
Rhizome
Complementary and alternative medicine
chemistry
Molecular Medicine
Steroids
Drug Screening Assays, Antitumor
Drugs, Chinese Herbal
Subjects
Details
- ISSN :
- 15206025
- Volume :
- 75
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Journal of natural products
- Accession number :
- edsair.doi.dedup.....9c6379e3b3d53ca5267a10b5a1882dff