Back to Search
Start Over
Design and synthesis of gene-directed caged cyclic nucleotides exhibiting cell type selectivity
- Source :
- Chemical communications (Cambridge, England). 57(46)
- Publication Year :
- 2021
-
Abstract
- We designed a new caging group that can be photoactivated only in the presence of a non-endogenous enzyme when exposed to 405 nm light. Because cells or tissues can be genetically tagged by an exogenously expressed enzyme, this novel method can serve as a strategy for adding targeting abilities to photocaged compounds.
- Subjects :
- Cell type
Light
Catalysis
Text mining
Materials Chemistry
Tumor Cells, Cultured
Humans
Nucleotide
Gene
chemistry.chemical_classification
Molecular Structure
business.industry
fungi
Metals and Alloys
food and beverages
General Chemistry
Photochemical Processes
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Enzyme
chemistry
Biochemistry
Ceramics and Composites
Nucleotides, Cyclic
Selectivity
business
HeLa Cells
Subjects
Details
- ISSN :
- 1364548X
- Volume :
- 57
- Issue :
- 46
- Database :
- OpenAIRE
- Journal :
- Chemical communications (Cambridge, England)
- Accession number :
- edsair.doi.dedup.....9cb607833be99b2fa42b56d4d1d9e8d3