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Table S8 from Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations

Authors :
Ralf Kittler
John D. Minna
Brian J. Druker
Kenneth D. Westover
Yan Liu
Shannon K. McWeeney
Daniel Bottomly
Christopher A. Eide
Michael Peyton
Kimberley Avila
Rahul K. Kollipara
Paul Yenerall
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Results of LentiMutate on KRAS-G12C cDNA and AMG 510 in the H358 cell line. Values shown are the averages of two biological replicates. The fold enrichment of "All nucleotides" is the sum of substitution rates for all nucleotides in the with doxycycline replicates divided by the sum of substitution rates for all nucleotides without doxycycline (parental) at one nucleotide position. Nucleotide w/ max error refers to the highest substitution rate for a single nucleotide at one nucleotide position.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....9ccd4efa6386652f6440eea21066e542
Full Text :
https://doi.org/10.1158/0008-5472.22362336.v1