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Outcome Prediction in Cerebral Venous Thrombosis: The IN-REvASC Score

Authors :: Klein, Piers
Shu, Liqi
Nguyen, Thanh N
Siegler, James E
Omran, Setareh Salehi
Simpkins, Alexis N
Heldner, Mirjam
Havenon, Adam de
Aparicio, Hugo J
Abdalkader, Mohamad
Psychogios, Marios
Vedovati, Maria Cristina
Paciaroni, Maurizio
von Martial, Rascha
Liebeskind, David S
Sousa, Diana Aguiar de
Coutinho, Jonathan M
Yaghi, Shadi
Neurology
ACS - Atherosclerosis & ischemic syndromes
ANS - Neurovascular Disorders
Source :: Journal of Stroke, 24(3), 404-416. Korean Stroke Society, Klein, Piers; Shu, Liqi; Nguyen, Thanh N; Siegler, James E; Omran, Setareh Salehi; Simpkins, Alexis N; Heldner, Mirjam; Havenon, Adam de; Aparicio, Hugo J; Abdalkader, Mohamad; Psychogios, Marios; Vedovati, Maria Cristina; Paciaroni, Maurizio; von Martial, Rascha; Liebeskind, David S; Sousa, Diana Aguiar de; Coutinho, Jonathan M; Yaghi, Shadi (2022). Outcome Prediction in Cerebral Venous Thrombosis: The IN-REvASC Score. Journal of stroke, 24(3), pp. 404-416. Korean Stroke Society 10.5853/jos.2022.01606
Publication Year :: 2022
Abstract: BACKGROUND We identified risk factors, derived and validated a prognostic score for poor neurological outcome and death for use in cerebral venous thrombosis (CVT). METHODS We performed an international multicenter retrospective study including consecutive patients with CVT from January 2015 to December 2020. Demographic, clinical, and radiographic characteristics were collected. Univariable and multivariable logistic regressions were conducted to determine risk factors for poor outcome, mRS 3-6. A prognostic score was derived and validated. RESULTS A total of 1,025 patients were analyzed with median 375 days (interquartile range [IQR], 180 to 747) of follow-up. The median age was 44 (IQR, 32 to 58) and 62.7% were female. Multivariable analysis revealed the following factors were associated with poor outcome at 90- day follow-up: active cancer (odds ratio [OR], 11.20; 95% confidence interval [CI], 4.62 to 27.14; P