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Node-Negative Non-small Cell Lung Cancer: Pathological Staging and Survival in 1765 Consecutive Cases
- Source :
- Journal of Thoracic Oncology. (10):1691-1696
- Publisher :
- International Association for the Study of Lung Cancer.
-
Abstract
- IntroductionThis study aimed to evaluate prognostic factors in patients with node-negative non-small cell lung cancer and to assess revised International Association for the Study of Lung Cancer staging recommendations for this group.MethodsA retrospective analysis of 1765 consecutive pathologically node-negative patients treated by surgical resection between 1984 and 2007 was performed. Survival analysis was conducted using the Kaplan-Meier method. The independence of prognostic factors was analyzed using multivariate Cox proportional hazards modeling.ResultsThe median age of patients was 68 years, and the average length of follow-up was 6.3 years. Perioperative mortality was 1.7%. The median survival was 6.5 years, with a 56% of the cohort surviving 5 years. Factors associated with poorer prognosis were male gender (hazard ratio [HR]: 1.30, p =
- Subjects :
- Pulmonary and Respiratory Medicine
Oncology
Adult
Male
medicine.medical_specialty
Lung Neoplasms
Staging
Survival
Pathological staging
Adenocarcinoma
Non-small cell lung cancer
Internal medicine
Carcinoma, Non-Small-Cell Lung
medicine
Humans
Lung cancer
Survival rate
Survival analysis
Aged
Neoplasm Staging
Retrospective Studies
Aged, 80 and over
Proportional hazards model
business.industry
Hazard ratio
Retrospective cohort study
Middle Aged
medicine.disease
Prognosis
Surgery
Survival Rate
Carcinoma, Squamous Cell
Carcinoma, Large Cell
Female
Lymph Nodes
Lung cancer staging
business
Follow-Up Studies
Subjects
Details
- Language :
- English
- ISSN :
- 15560864
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Journal of Thoracic Oncology
- Accession number :
- edsair.doi.dedup.....9ce2c8a1f85c7f2f438aa520a0442e1b
- Full Text :
- https://doi.org/10.1097/JTO.0b013e31822647fd